In Genome Databases you may check the 'Gene server'-toggle to build a PT-Server which is based on the sequences of the single genes (and intergene regions) of all organisms.
Such a PT-Server allows to perform similarity searches and probe design/match for single genes (in opposite to whole genomes with a "normal" PT-Server).
When designing probes with such a gene PT-Server you always have to validate these probes against a PT-Server build upon complete genome sequences, otherwise you will get incorrect results for all probes matching at beginning/end of a gene.
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